Physiological mechanisms of action of vitamin D in oral tissues and organs and the possibility of its use in preventive dentistry (literature review)

Vitamin D has a variety of effects on oral tissues and organs. Cholecalciferol is involved in the processes formation enamel dentin, metabolism jaw bone tissue, local immunity antitumor reactions. The functional features vitamin reveal possibility dental pathology prevention. Objective. To study literature data effect organs using as drug prevention diseases. Materials methods. review analysis literary sources was carried out by keywords electronic resources Scopus, Web Science, MedLine, Cochrane Library, RSCI databases. Russian foreign were used. conducted between August 2021 March 2022. Results. Randomized studies prove that receptors for (colecalciferol) are found surface almost all cells, which explains pleiotropic human body. Colecalciferol substitutive dentin foci demineralization. active metabolite an tissues, anti-inflammatory antimicrobial action periodontal disease. influences osseointegration during implantation, osteogenesis osteolysis orthodontic treatment. Conclusion. various cavity, gives to include cholecalciferol clinical guidelines diseases prophylaxis.